First-in-human clinical trials at Siteman Cancer Center to evaluate universal CAR T-cell therapies

This summer, the latest generation of CAR T-cell therapies for patients diagnosed with lymphoma, myeloma or leukemia get underway in clinical trials at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis. The cancer center was one of the first in the U.S. to offer CAR T-cell therapy for the treatment […]
Newly approved drug effective against lung cancer caused by genetic mutation

The new drug sotorasib reduces tumor size and shows promise in improving survival among patients with lung tumors caused by a specific DNA mutation, according to results of a global phase 2 clinical trial. The drug is designed to shut down the effects of the mutation, which is found in about 13% of patients with […]
Personalized cancer vaccines for breast, pancreatic cancers show promise

Researchers at Washington University School of Medicine in St. Louis have shown that personalized cancer vaccines made using DNA…
Cell-based immunotherapy shows promise against melanoma

A new study from Washington University School of Medicine in St. Louis demonstrates, in mice and human cells, that a cell-based…
Chemo for glioblastoma may work better in morning than evening

Shown are the MRI scans of the brain of a participant in a clinical trial evaluating chronotherapy — or the timed delivery of…