Clinical Trials Update

Siteman Kids is the First Site of Multicenter CAR-T Trial for Autoimmune Diseases

  Access to the novel immunotherapy ­­— which “has the potential for cure” — is the latest offering by the national leader in pediatric hematology, oncology, and cell therapies. Siteman Kids at St. Louis Children’s Hospital, along with WashU Medicine in St. Louis, is the first site to test a novel immunotherapy drug for the […]

Immunotherapy improves survival of patients with locally advanced head and neck cancer

Approved drug that revolutionized melanoma treatment may change standard of care for yet another cancer type Research presented at the annual meeting of the American Association for Cancer Research (AACR) in April provides the strongest clinical evidence to date that standard of care therapy could soon be updated for the treatment of resectable locally advanced […]

New Clinical Trials Open for Sarcomas and Solid Tumors

Two exciting early phase clinical trials are underway at Siteman Cancer Center, based at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis, that leverage novel classes of drugs and exploit how proteins can be targeted and/or removed to stop uncontrolled cell division that occurs in sarcomas and solid tumors. For BRAF B600 […]

Whole Genome Sequencing for AML/MDS Risk Stratification

ChromoSeq now covered by Medicare; Two Clinical Trials Also Open Two novel clinical trials for patients diagnosed with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) are open and enrolling patients at Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis. The clinical trials are utilizing a breakthrough whole-genome […]

Siteman Cancer Center Advances Head and Neck Tumor Discovery

Soon, a global, stage III randomized clinical trial could result in a paradigm shift in how certain head and neck cancers are treated. The clinical trial, called KEYNOTE-689 and overseen by the Merck pharmaceutical company, is the result of specific research initiated by head and neck cancer specialists at Siteman Cancer Center at Barnes-Jewish Hospital […]

Treating Multiple Myeloma — New Immunotherapies

  Multiple myeloma has long vexed medical researchers because of the cancer’s specific ability to both weaken and “hide” from a patient’s own immune system. The result is that while many treatments have been able to treat the disease for some time, patients subsequently relapse. But newer medications now can control the disease for extended […]

New Clinical Trials for Prostate, Kidney Cancers

Siteman Cancer Center has three new clinical trials open focused on prostate and kidney cancers. The first, a Phase II clinical trial testing a neoadjuvant immunotherapy treatment for prostate cancer, is available for men who have been diagnosed with localized prostate cancer. The study will evaluate the use of atezolizumab alone and in combination with […]